![]() ![]() ![]() It is also less prone to ion suppression and matrix effects compared to ESI and APCI and typically has a wide linear dynamic range. The benefit of APPI is that it ionizes molecules across a broad range of polarity and is particularly useful for ionization of low polarity molecules for which other popular ionization methods such as electrospray ionization (ESI) and atmospheric pressure chemical ionization (APCI) are less suitable. The sample is usually a solvent spray that is vaporized by nebulization and heat. Molecules are ionized using a vacuum ultraviolet (VUV) light source operating at atmospheric pressure (105 Pa), either by direct absorption followed by electron ejection or through ionization of a dopant molecule that leads to chemical ionization of target molecules. Atmospheric pressure photoionization chamberĪtmospheric pressure photoionization (APPI) is a soft ionization method used in mass spectrometry (MS) usually coupled to liquid chromatography (LC).
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |